The Science of Cannabis Near Me in Spokane & Clarkston
Discover the fascinating science behind cannabis, from cannabinoids to terpenes, and how they interact with your body. At Sativa Sisters, we’re committed to factual, scientific information to empower your cannabis journey in Spokane and Clarkston, WA.
Cannabinoids: The Active Compounds
Cannabinoids are the chemical compounds in cannabis that produce its effects. The two most well-known are:
- THC (Tetrahydrocannabinol): The psychoactive compound responsible for the "high." It binds primarily to CB1 receptors in the brain and some CB2 receptors.
- CBD (Cannabidiol): Non-psychoactive, known for potential wellness benefits like reducing anxiety. It has low affinity for CB1 and CB2 receptors, modulating them indirectly.
- CBN (Cannabinol): Mildly sedative, often found in aged cannabis. It has weak affinity for CB1 and CB2 receptors.
- CBG (Cannabigerol): A non-psychoactive precursor to other cannabinoids, potentially supporting nerve health and anti-inflammatory effects. It acts as an antagonist at CB1 and CB2 receptors.
- CBC (Cannabichromene): Non-psychoactive, may promote anti-inflammatory and pain-relief properties. It has weak binding to CB1 and CB2 receptors but acts as a TRPA1 agonist.
- THCV (Tetrahydrocannabivarin): Found in some strains, it may suppress appetite and offer mild psychoactive effects at higher doses. It acts as a CB1 antagonist and CB2 agonist.
Over 100 cannabinoids exist, each with unique effects. Visit our home page to explore THC- and CBD-dominant options in our Spokane and Clarkston stores.
Terpenes: The Aroma and Flavor
Terpenes are aromatic compounds that give cannabis its distinct smells (e.g., citrus, pine). They also influence effects via the "entourage effect." Common terpenes include:
- Caryophyllene: Spicy, peppery; found in Girl Scout Cookies, acts as a CB2 receptor agonist, potentially offering anti-inflammatory benefits in a way that most other terpenes do not seem to.
- Myrcene: Earthy, relaxing; found in strains like OG Kush, may enhance sedative effects.
- Limonene: Citrusy, uplifting; in strains like Super Lemon Haze, may reduce stress.
- Pinene: Piney, alertness-enhancing; in Blue Dream, may improve focus.
- Linalool: Floral, calming; found in Lavender strains, may promote relaxation.
- Humulene: Woody, earthy; in White Widow, may have anti-inflammatory properties.
- Terpinolene: Sweet, herbal; in Jack Herer, may offer mild sedative effects.
- Ocimene: Sweet, herbaceous; in Strawberry Cough, may have antifungal benefits.
Explore terpene profiles on our home page to find your perfect strain.
The Endocannabinoid System
The endocannabinoid system (ECS) is a complex network of receptors, enzymes, and endocannabinoids in the human body that plays a crucial role in maintaining homeostasis, or balance. Discovered in the 1990s, the ECS regulates various physiological processes, including mood, appetite, pain sensation, immune response, and sleep. It consists of two main types of receptors: CB1, primarily found in the brain and central nervous system, and CB2, located mainly in the peripheral nervous system, immune cells, and organs.
Endocannabinoids, like anandamide and 2-AG, are naturally produced by the body and bind to these receptors to signal the ECS to take action. Enzymes such as FAAH and MAGL break down these endocannabinoids once they've served their purpose. Cannabis compounds, or phytocannabinoids, mimic these endocannabinoids, interacting with the ECS to produce effects. For example, THC binds strongly to CB1 receptors, leading to psychoactive effects, while CBD modulates receptor activity without direct binding.
Research suggests the ECS influences stress response, neurodevelopment, and inflammation. Dysregulation of the ECS has been linked to conditions like chronic pain, anxiety, and autoimmune disorders. Additionally, the ECS interacts with terpenes like caryophyllene, which uniquely binds to CB2 receptors, potentially enhancing anti-inflammatory effects. At Sativa Sisters, we use this scientific understanding to guide our product selection, helping customers in Spokane and Clarkston find options that support their wellness goals. Learn more in our Cannabis 101 guide.
Why Trust Sativa Sisters?
Our Spokane Valley and Clarkston stores carry lab-tested products from I-502 licensed farms, ensuring quality and compliance. Curious? Shop now.
Sources: National Institutes of Health (NIH), Washington State Liquor and Cannabis Board (LCB).